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CYTOCHROME P450 IA1
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DeCS
Descriptor
English
:
Cytochrome P-450 CYP1A1
Descriptor
Spanish
:
Citocromo P-450 CYP1A1
Descriptor
Portuguese
:
Citocromo P-450 CYP1A1
Synonyms
English
:
7-Ethoxyresorufin O-Deethylase
CYP 1A1
CYP1A1 Protein
Cytochrome P450 IA1
Ethoxyresorufin Dealkylase
Ethylresorufin O-Deethylase
Cytochrome P 450 CYP1A1
CYP1A1
Ethoxyresorufin O-Deethylase
EROD
Tree Number:
D08.244.453.005.332
D08.244.453.100.500
D08.811.682.690.708.170.010.277
D08.811.682.690.708.170.020.500
D12.776.422.220.453.010.332
D12.776.422.220.453.100.500
Definition
English
:
A liver microsomal
cytochrome
P-450 monooxygenase capable of biotransforming
xenobiotics
such as polycyclic
hydrocarbons
and halogenated
aromatic hydrocarbons
into carcinogenic or mutagenic compounds. They have been found in
mammals
and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity.
Indexing Annotation
English
:
do not confuse with other
cytochrome
P-450 CYP's
History Note
English
:
97; was ETHOXYRESORUFIN O-DEETHYLASE (NM) 1979-96
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
33008
Unique Identifier:
D019363
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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